|
|
|
|
|
|
Above: B103 - set of three model plates Below: B101 under UV light
|
|
B103 Bacterial Transformation Models,
set of 3 Foreign genes can be inserted into the cells of an organism to produce and harvest specific proteins. This is known as genetic transformation. The biotechnology industry uses E.coli extensively to generate potentially beneficial products such as insulin and Human Growth Hormone.
These model plates
demonstrate a native E.coli culture and the results of transforming E.coli with genes that code
for Green Fluorescent Pigment (GFP) and pBLU, a dark blue chromophore. Made from durable resin, these models can be used over and over again. Explanatory notes are included. A long wavelength UV light is required to observe the fluorescent glowing effect in the GFP model. Individual model plates are available if required: B100 - E.coli bacterial model plate without transformation. E.coli is the most thoroughly studied cellular organism because it is very convenient to examine - it grows rapidly, doesn't require a lot of care, and is easy to store. Much of what has been learnt can be generalised to the cell systems of plants and animals, including humans.
B101 - E.coli bacterial model plate that has undergone GFP transformation B102 - E.coli bacterial model plate that has undergone pBLUE transformation The jellyfish, Aequorea victoria, glows in the dark because it has a gene that codes for Green Fluorescent Pigment (GFP). E.coli that has been transformed with this gene will produce GFP and glow in the dark under ultra violet light. When transformed with the pBLUEgene, E.coli turns dark blue. These two genes are often used in research as visual aids. Transformed E.coli are much easier to identify when they glow or change colour. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
